Stains and spills don’t negatively impact the Travelguard. When treating the Travelguard you should first run it through a high-heat dryer cycle before putting it in the washing-machine. The Travelguard requires no special accommodations for washing and may be washed like any other bed sheet. The Travelguard is tested for 10,000 high heat laundry cycles and can also be dry cleaned, safely.